Biological nanodevices

Science and technology have made it possible to design and manufacture macromolecules (such as nucleic acids and proteins) and their structure and function are becoming ever better understood. In the coming 10 years a new phase will appear wherein complex molecular systems are designed, made and studied, consisting of multiple macromolecules that operate in concert as nano-devices with novel functionalities. This will lead to highly sophisticated adaptive molecular systems and devices that are able to function with and within live biological systems. Novel bio-sensory and bio-actuation functionalities are expected, resulting from developments in bionanotechnology, chemical biology, biophysics, supramolecular chemistry, bottom-up synthetic biology, nanophotonic sensors, and nanomedicine.

Potential embodiments include smart materials (e.g. bio-adaptive nano-materials for regenerative medicine and cell culturing, responsive drug carriers, multivalent scaffolds for sensing, diagnostics and regulation), smart devices (e.g. patches, probes, catheters, implants), and combinations thereof.


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